Psychedelic experience in the modern era has always been queer—not just in the sense of being enchanted, wayward, and weird, but in the more concrete sense that queerfolk have fundamentally shaped the substance, style, and spirituality of the psychedelic underground.

Doctors, patients, and the government agencies that fund research are often suspicious of a drug known to cause hallucinations, as they have been of psychedelics like psilocybin and ecstasy, despite their potential for treating depression or anxiety. Each tends to show fast results after a single dose, like ketamine.